142nd APHA Annual Meeting and Exposition

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296344
NICHD Global Network Antenatal Corticosteroids Trials (ACT)

142nd APHA Annual Meeting and Exposition (November 15 - November 19, 2014): http://www.apha.org/events-and-meetings/annual
Monday, November 17, 2014 : 9:30 AM - 9:50 AM

Pierre Buekens, MD , Tulane University School of Public Health and Tropical Medicine, New Orleans, LA
Fernando Althabe, MD , Institute for Clinical Effectiveness and Health Policy
Jose Belizán, MD , Institute for Clinical Effectiveness and Health Policy
Agustina Mazzoni , Institute for Clinical Effectiveness and Health Policy
Mabel Berrueta , Institute for Clinical Effectiveness and Health Policy
Jennifer Hemingway-Foday, MPH , RTI International
Marion Koso-Thomas, MD, MPH , NICHD
Elizabeth McClure, PhD , RTI International
Elwyn Chomba, MBBS , University of Zambia
Ana Garces, MD , FANCAP
Shivaprasad S. Goudar, MD, MHPE , Global Network for Women's and Children's Health Research Site 8, J N Medical College, Belgaum Karnataka, India
Bhala Kodkany, MD , KLE's JN Medical College
Sarah Saleem, MBBS , Aga Khan University
Omrana Pasha, MD, MPH , Aga Khan University
Archana Patel, MD, PhD , Indira Ghandi Medical School
Fabian Esamai, MBBS , Moi University
Waldemar Carlo, MD , University of Alabama
Nancy Krebs, MD , University of Colorado at Denver
Richard Derman, MD MPH , Dept. of Obstetrics & Gynecology, Christiana Care Health System, Newark, DE
Robert Goldenberg, MD , Columbia University
Patricia Hibberd, MD , Harvard University
Edward Liechty, MD , Indiana University
Linda Wright, MD , NICHD
Eduardo Bergel
Alan Jobe, MD. PhD , Cincinnati Children's Hospital
Audio (mp3) recording Recorded Presentation (mp4)
We performed a multi country cluster randomized controlled trial to evaluate whether a multifaceted intervention to increase the use of antenatal corticosteroids at health facilities and communities would reduce neonatal mortality at 28 days of life in preterm infants. 102 clusters in Argentina, Guatemala, Kenya, India, Pakistan, and Zambia were randomized. In the intervention clusters, kits containing vials of dexamethasone, syringes, gloves, and instructions for administration were distributed. In the intervention clusters we also did (1) diffuse recommendations for antenatal corticosteroids use to health providers, (2) train health providers on identification of women at high risk of preterm birth, (3) provide reminders to health providers on the use of the kits, and (4) use a color-coded tape to measure uterine height to estimate gestational age in women with unknown gestational age.

Learning Areas:

Clinical medicine applied in public health
Conduct evaluation related to programs, research, and other areas of practice
Epidemiology
Public health or related research

Learning Objectives:
Describe a multi country cluster randomized controlled trial to evaluate whether a multifaceted intervention to increase the use of antenatal corticosteroids at health facilities and communities would reduce neonatal mortality at 28 days of life in preterm infants.

Keyword(s): Perinatal Health, International MCH

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am the PI of the study
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

Back to: 3048.0: International Maternal, Neonatal & Child Health