Transitioning from a proprietary electronic data capture (EDC) system to an open-source (OS) platform
Wednesday, November 6, 2013
: 1:10 p.m. - 1:30 p.m.
Background: Current EDC systems boast secure and user-friendly online survey management and data monitoring. However, these systems often fail to meet the difficult integration requirements of multidisciplinary and collaborative research projects. To meet these requirements for an autism research project, we migrated and re-packaged our own proprietary EDC system into an open-source, web-based integrated EDC system called RexAcquire. Methods: We (1) defined the data collection needs of a large-scale autism research project; (2) developed a new code base; (3) obtained an open-source license; (4) made the code freely available through BitBucket; (5) converted the pre-existing configuration, user and assessment data into the new OS-compatible format; and (6) evaluated the platform. Results: Users reported a need for a self-administered EDC, where patients could directly submit answers to common research forms. Interactive user configurability, reusability of study instruments, sophisticated form configuration, and the ability to query across multiple studies and data types were among the top requested features for RexAcquire. The data conversion proved to be challenging, requiring significant migration plans. The software is freely available for download, use, and modification as part of the OS RexDB package at www.RexDB.org. Conclusions: The results of transitioning from a non-integrated EDC system to the OS RexAcquire and RexDB platforms for a large-scale autism research study were successful. RexAcquire supported secure interactive user configurability, the efficient reuse of research instruments from multiple studies and data types, and the migration of data into an iDMS (RexDB). Future support for multiple languages and offline access should be considered for international research projects.
Communication and informatics
Social and behavioral sciences
Discuss the limitations of existing EDC systems.
Describe the purpose of RexAcquire including its integration with the Research Exchange Database (RexDB®).
Outline the transition to an OS platform for autism research.
List the benefits of a web-accessible EDC system that automatically pushes research data into an Integrated Data Management System (iDMS).
Keyword(s): Data Collection, New Technology
Presenting author's disclosure statement:
Qualified on the content I am responsible for because: I am the Director of Platform Architecture and have several years of experience in analysis, scientific research, software development, data modeling and project management.
Any relevant financial relationships? Yes
|Name of Organization
||Type of relationship
|Prometheus Research, LLC
Employment (includes retainer)
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines,
and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed
in my presentation.