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Yuda Chongpison, MS, MBA, College of Pharmacy, The University of Arizona, P.O. Box 210207, 1703 E. Mabel Street, Tucson, AZ 85721, 520 670 0040, chongpison@pharmacy.arizona.edu, Kimberly A. Lowe, MS, Mel and Enid Zuckerman College of Public Health, The University of Arizona, 1501 N. Campbell Ave., Tucson, AZ 85724, Scott Going, PhD, The Deparment of Nutritional Science, The University of Arizona, 238 Shantz Building, Tucson, AZ 85721, and Zhao Chen, PhD, MPH, Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, PO Box 245203, 1540 E. Drachman St., Tucson, AZ 85724.

Introduction: BMI is a surrogate measure of body fatness and is used to identify obesity in children and adults. Using Dual-energy X-ray Absorptiometry (DXA) as the gold standard, we evaluate the association of BMI with TPBF. Methods: Baseline data collected from the Women Health Initiative (WHI) study were used for these analyses, dichotomously stratified at age 65 and categorized as non-Hispanic whites, blacks, and Hispanics. Obesity measurements were classified as normal weight: BMI <25, overweight: BMI >25 and <30, obese: BMI >30. Sensitivity and specificity values for the relationship between BMI and TPBF were determined using the standard 38% TPBF cutoff. Pearson's correlation, simple linear and break-point regression models were also conducted to evaluate the relationships between BMI and TPBF. Results: Correlations between BMI and TPBF for non-Hispanic-whites, blacks and Hispanics were 0.753, 0.746, and 0.691, respectively. Sensitivity and specificity showed that BMI is a good proxy to identify obesity among WHI subjects, across all age and ethnic groups. Results from break-point regression indicated a significant change in the strength of the relationship between BMI and TPBF at BMI=27.7. Conclusions: Our analyses show that BMI and TPBF are highly correlated among all ethnic and age groups and BMI may be a good proxy for normal to overweight postmenopausal women. However, since the WHI is not a population-based sample, more studies are needed to confirm our findings.

Learning Objectives: Learning Objective

To evaluate if BMI (kg/m
• is a good proxy of TPBF among different age and ethnic/racial groups of women in the Women Health Initiative (WHI).

Keywords: Obesity, Aging

Presenting author's disclosure statement:

Not Answered