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American Public Health Association
133rd Annual Meeting & Exposition
December 10-14, 2005
Philadelphia, PA
APHA 2005
 
3060.0: Monday, December 12, 2005 - 8:45 AM

Abstract #107273

Association between use of antimicrobial use in food animals and antimicrobial resistance among bacteria isolates from humans, and the human health consequences of such resistance

Fred Angulo, DVM, PhD, NARMS Activity, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333 and Stacy Holzbauer, DVM, MPH, Foodborne and Diarrheal Disease Branch, National Center for Infectious Diseases, Center for Disease Control and Prevention, 1600 Clifton Road, MS-D63, Atlanta, GA 30333, 404-371-5334, cyi3@cdc.gov.

Several lines of evidence indicate that use of antimicrobial agents in food animals is associated with antimicrobial resistance among bacteria isolated from humans. The use of antimicrobial agents in food animals is most clearly associated with antimicrobial resistance among Salmonella and Campylobacter isolated from humans, but also appears likely among enterococci, Escherichia coli, and other bacteria. Evidence is accumulating that the antimicrobial resistance among bacteria isolated from humans resulting from use of antimicrobial agents in food animals is leading to human health consequences. These human health consequences include: (1) infections that would not have otherwise occurred, and (2) increased frequency of treatment failures and increased severity of infection. Increased severity of infection includes longer duration of illness, increased frequency of bloodstream infections, increased hospitalization and increased mortality. To mitigate the public health problem of antimicrobial resistance associated with the use of antimicrobial agents in food animals, continued efforts are needed on the part of the medical, veterinary, and public health community to implement more precise guidelines on the use of antimicrobial agents in food animals.

Learning Objectives:

Keywords: Antibiotic Resistance, Food Safety

Presenting author's disclosure statement:

I wish to disclose that I have NO financial interests or other relationship with the manufactures of commercial products, suppliers of commercial services or commercial supporters.

[ Recorded presentation ] Recorded presentation

Agriculture, Animal Industry, and Public Health

The 133rd Annual Meeting & Exposition (December 10-14, 2005) of APHA