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Outbreak of Crimean Congo Hemorrhagic Fever (CCHF) in Kosova, 1995-2001

Ariana Kalaveshi, MD, MPH1, Gjyle Mulliqi-Osmani, MD, PHD2, Drita Salihu, MD, MPH3, Teuta Osmani-Vllasolli, MD1, Alisa Diggs-Gooding, PA-C, MPH4, and Vjollca Berisha, MD, MPH4. (1) Epidemiology, National Institute of Public Health Of Kosova, Rrethi i spitalit P.N., Prishtine, Kosove, Yugoslavia, 38138541432, ari_kala@yahoo.com, (2) Microbiology, National Institute of Public Health Of Kosova, Rrethi i spitalit P.N., Prishtine, Kosove, Yugoslavia, (3) Social Medicine, National Institute of Public Health Of Kosova, Rrethi i spitalit P.N., Prishtine, Kosove, Yugoslavia, (4) Division of Epidemiology Biodefense Preparedness and Response, Maricopa County Department of Public Health, 1010 E McDowell Road Suite 300, Phoenix, AZ 85006

Retrospective analysis of surveillance data from the Institute of Public Health in Prishtina, Kosova demonstrates an outbreak of CCHF between 1995-2001 with a total number of 129 reported cases and 19 deaths (16% case fatality). The territory of Kosova, an endemic zone for CCHF, registered its first documented case in 1954.

Due to high infectiousness, severe clinical picture, and high lethality it was necessary to determine case frequency, geographic spread and risk factors in order to initiate preventive measures.

During 1995, a widespread outbreak was documented with 65 confirmed CCHF cases and 7 deaths. A year later, 23 cases (resulting in 5 deaths) were documented. In the following years (1997-2000) only sporadic cases were registered. During the latest outbreak in 2001 there were 31 confirmed cases resulting in 7 deaths.

Males were more affected, accounting for 61% of total cases. Among occupations, farmers comprised 40% and housewives 30% of total cases. All age groups were affected.

Epidemiological investigation indicates that tick bites account for 57% of exposures, direct contact for 11% and the remaining 32% are unknown. Seasonal distribution of the disease was during spring and summer, with a peak of cases during months of June, July and August.

The preceeding analysis provides a profile of CCHF morbidity and mortality over a five-year period during three outbreaks. This created a basis for further development of surveillance systems design to detect and prevent similar outbreaks as well as to educate the general population and local health care providers.

Learning Objectives:

Keywords: Infectious Diseases, Surveillance

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

Outbreak Investigations

The 132nd Annual Meeting (November 6-10, 2004) of APHA