S. Tu, MD, MPH¹, Vicky M. Taylor, MD, MPH², Yutaka Yasui, PhD³, Elizabeth Acorda, BA³, Mei-Po Yip, RN, PhD⁴, Alan Chun, MD⁵, and Roshan Bastani, PhD⁶. (1) Department of Medicine, University of Washington, Harborview Medical Center, Box 359780, 325 Ninth Ave, Seattle, WA 98104, 206-731-4236, shinping@u.washington.edu, (2) Cancer Prevention Program, Fred Hutchinson Cancer Research Center, PO Box 19024, MP702, 1100 Fairview Avenue N., Seattle, WA 98109-1024, (3) Cancer Prevention Research Program, Fred Hutchinson Cancer Research Center, PO Box 19024, MP702, 1100 Fairview Avenue N., Seattle, WA 98109-1024, (4) Harborview Medical Center, University of Washington, 325 Ninth, Seattle, WA 98104, (5) International Community Health Services, PO Box 3007, Seattle, WA 98114, (6) University of California - Los Angeles, 650 S. Charles Young Dr., P.O. Box 956900, A2- 125 CHS, Los Angeles, CA 90095

Colorectal cancer (CRC) is the second leading cause of cancer mortality in the US. Compelling studies indicate that fecal occult blood testing (FOBT) can reduce mortality due to CRC; however, the few surveys conducted in Asian American communities reveal low rates of CRC screening. To promote FOBT, we are conducting a randomized controlled trial to evaluate a clinic-based intervention with Chinese American patients. International Community Health Services (ICHS), a community based agency in Seattle, has a clinic located in the heart of Chinatown that serves a predominantly Asian American clientele. Chinese patients at ICHS who speak Cantonese, Mandarin or English, are 50-78 years of age, have no prior history of colorectal cancer or end stage diseases, and have not had FOBT screening in the last 12 months are eligible for the study. At the index clinic visit, participants are randomly selected for the intervention or control group (usual care). The intervention consists of a motivational and educational video as well as pamphlets delivered by a health educator. A total of 421 patients will be randomized into the intervention trial. The primary outcome of this study is FOBT screening within the 6 months after randomization. Analysis comparing FOBT screening rates between the intervention and control groups will first be conducted using Chi Square analysis. Unconditional logistic regression techniques will then be performed to estimate the independent effects of factors associated with FOBT participation. We will describe the content of the intervention and present the preliminary results of this intervention trial.

Learning Objectives:

• Describe the US incidence and mortality due to colorectal cancer
• Describe the content of a culturally appropriate intervention to promote fecal occult blood testing

Keywords: Cancer Screening,

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.