Tobacco use poses China°¦s most critical public health problem.  Two-thirds of China°¦s 330 million smokers are unaware or do not believe there is a link between smoking and disease risk.  Access to information about the health consequences of smoking is vital to tobacco use reduction in China.  We examined sources of health information commonly accessed and investigated their relationships with tobacco use and SES among adults in China. Self-report questionnaires on tobacco use and related health behaviors were administered to students and their parents in four regions and seven corresponding cities: North-East (Harbin, Shenyang), Center (Wuhan), South-West (Chengdu, Kunming), and Coastal (Hangzhou, Qingdao). The sample consisted of 3858 male adults and 4048 female adults.  Logistic regression models were used to investigate the impact of SES on sources of health information acquisition.  Regional variations in health information acquisition were also investigated. Prevalence rates for current tobacco use in the seven cities ranged from 72.3% to 79.6% for male adults and 3.7% to 7.3% for female adults.  Results from logistic regression models demonstrated that SES significantly impacted health information acquisition channels on current smoking behavior among male adults.  Regional and city differences on use of health information acquisition sources were also detected.  Variations in health information acquisition were detected across levels of SES status and cities, or regions.  Disparities in current smoking behavior at the individual, city, and regional, levels were also observed. Identifying effective sources of health information acquisition for adults at various SES levels may reduce tobacco-related disease in China.