The 131st Annual Meeting (November 15-19, 2003) of APHA

The 131st Annual Meeting (November 15-19, 2003) of APHA

3050.0: Monday, November 17, 2003 - Board 6

Abstract #63982

Matching eligible HIV/AIDS patients with available clinical research opportunities: The Study-Link project

Diana S. Catz, PhD, MPH, Héctor Bárcena, Pearl Cedeño, and Jonathan N. Tobin, PhD. Clinical Directors Network, Inc., 54 West 39th Street 11th Floor, New York, NY 10018, 212-382-0699 Ext 230, dcatz@CDNetwork.org

Study-Link is a combination of a database of all recruiting HIV/AIDS clinical and behavioral trials in the city of New York, a dedicated telephone counseling line, outreach efforts and a network of academic research centers and community-based organizations that conduct research in HIV/AIDS and cross-refer patients. We compared two 18-months periods: 2/1/00 to 7/31/01 and 8/1/01 to 1/31/03. During the last period we switched from outreach workers to peer outreach workers. Results: Over three years, 460 patients were referred to clinical trials. We observed an increase in the proportion of African Americans patients referred to clinical trials (46% to 62%), while Caucasian and Hispanics patients decreased (14 to 10 %, and 31% to 26% respectively, p<0.01). Female patients decreased from 57 % to 43% (p<0.01) and 26% of the patients had CD4 counts < 200, and 47% had viral loads <400. Patients with weight problems increased significantly (p<0.001), and the proportion of patients not using any antiretroviral medication also increased, (18 to 25 %, p=0.07). Data from intake surveys in the last period indicated that: 70 % of the patients were depressed, 21% abused alcohol, 51% had memory problems, 71 % were under stress and 28% were co-infected with Hepatitis C. Conclusions: This project has successfully engaged hard-to-reach populations into HIV/AIDS clinical studies. Co-morbidities, including stress, depression and dementia, are common among people living with HIV/AIDS, and may represent significant barriers to clinical trial participation. Supported by Ryan White Title I, HIV CARE services # 98-OCB-706.

Learning Objectives:

Keywords: HIV/AIDS, Ethnic Minorities

Related Web page: www.CDNetwork.org

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

Research and Evaluation Poster Session

The 131st Annual Meeting (November 15-19, 2003) of APHA