The 130th Annual Meeting of APHA

4048.0: Tuesday, November 12, 2002 - 9:30 AM

Abstract #50071

Pregnancy Complications, Method of Delivery, and Infant Mortality due to Respiratory Distress Syndrome in the United States

Pradip K Muhuri, PhD, ORM, National Center for Health Statistics, 6525 Belcrest Road, Hyattsville, MD 20782, 301-458-4391, pmuhuri@cdc.gov, Marian F. MacDorman, PhD, Statistician, National Center for Health Statistics, National Center for Health Statistics, 6525 Belcrest Road Room 820, Hyattsville, MD 20782, and Trena M. Ezzati-Rice, MS, National Center for Health Statistics, CDC, Office of Reserch and Methodology, 6525 Belcrest Road, Room 915, Hyattsville, MD 20782.

This paper uses multivariate regression analysis to examine the effects of pregnancy complications and method of delivery on infant mortality from respiratory distress syndrome (RDS) for various race/ethnic groups in the US. The study is based on the linked birth/infant death data sets and includes singleton preterm births in the US from the 1995-97 cohorts. Cesarean births had more than twice the odds of RDS death, when compared to vaginal births. This difference was observed for all race/ethnic groups studied. For each method of delivery (vaginal or Cesarean), black infants had about twice the odds of RDS mortality as white infants. Hispanic and Asian/Pacific Islander infants had lower odds of death from this cause; the decreased odds estimated for American Indians were not statistically significant. Maternal diabetes and hypertension appear to decrease rather than increase the risk of death due to RDS. These findings corroborate the results of earlier studies, which found that the large placentas of infants born to diabetic mothers and maternal chronic stress during pregnancy help accelerate lung maturation resulting in reduced incidences of RDS. The Cesarean- and race-effects on RDS mortality do not appear to be confounded with socioeconomic controls. The health services implications of these results are discussed.

Learning Objectives:

Presenting author's disclosure statement:
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

Emerging Issues in Infant and Perinatal Mortality in the United States

The 130th Annual Meeting of APHA