A case-control study was conducted. Cases were women younger than 70, with newly diagnosed invasive cervical cancer, who had been residing for at least the past one year in the metropolitan area of Guadalajara, Mexico. They were selected from 5 hospitals belonging to the Mexican National Health System. Control were selected from current attendants at the same Health Centers where the case received care. Analysis included 143 cases and 311 controls. Information was obtained through a standardized personal interview. Multivariate logistic regression was used to obtain maximum likelihood estimates of the relative risk. A large proportion of subjects had 7 or more pregnancies (60.1% of the cases vs. 47.6% of the controls). An association with number of pregnancies was observed after adjustment for age, education, age at first intercourse and number of sexual partners, with risk rising to 2.6 (95% C.I.=1.1-5.9) for those with 7-9 pregnancies when compared with women with 1-3 pregnancies. Pregnancy associations appeared to relate to the number of livebirths. In contrast, no association was observed with either spontaneous or induced abortion. A decreased risk was observed for women who reported 2 or more cesarean sections, however, it was not significant (RR=0.6). A reduction in completed family size could have a favorable impact on the incidence of cervical cancer in Mexico.
Learning Objectives: Analyse the relationship between reproductive factors and cervical cancer in a population where a large proportion of the women has had multiple pregnancies
Keywords: Cervical Cancer,
Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: None
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.